1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester - Names and Identifiers
Name | 1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester
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Synonyms | Methyl 7-aza-2-oxindole-4-carboxylate 7-Aza-2-oxindole-4-carboxylic acid methyl ester methyl 2-oxo-1H,2H,3H-pyrrolo[2,3-b]pyridine-4-carboxylate Methyl 2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-4-carboxylate 1H-Pyrrolo[2,3-b]pyridine-4-carboxylicacid,2,3-dihydro-2-oxo-,Methylester 1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester Methyl 2-oxo-1-((2-(triMethylsilyl)ethoxy)Methyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-4-carboxylate
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CAS | 1190313-98-4
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1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester - Physico-chemical Properties
Molecular Formula | C9H8N2O3
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Molar Mass | 192.17 |
Density | 1.351±0.06 g/cm3(Predicted) |
Boling Point | 435.3±45.0 °C(Predicted) |
pKa | 12.15±0.20(Predicted) |
Storage Condition | Room Temprature |
1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester - Introduction
2,3-dihydro-2-oxo-7-azaindole -4-carboxylic acid methyl ester, chemical formula C9H11NO3, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2,3-dihydro-2-oxo-7-azaindole -4-carboxylic acid methyl ester is a colorless or slightly yellow liquid.
-Melting point: approximately 24-25°C.
-Boiling point: approximately 103°C.
-Density: about 1.20g/cm3.
-Solubility: Soluble in most common organic solvents.
Use:
-2,3-dihydro-2-oxo-7-azaindole -4-carboxylic acid methyl ester is mainly used as an intermediate in organic synthesis and can be used to synthesize various nitrogen-containing organic compounds.
-It also has certain applications in medicinal chemistry and pesticide synthesis.
Preparation Method:
-2,3-dihydro-2-oxo-7-azaindole -4-carboxylic acid methyl ester has relatively many preparation methods. One of the commonly used methods is to react methyl indole -4-carboxylate with silver nitrite to give methyl 2,3-dihydro-2-oxo-7-nitrite silver indole -4-carboxylate, which is then reduced to methyl 2,3-dihydro-2-oxo-7-azaindole -4-carboxylate by hydrogenation reduction.
Safety Information:
-Methyl 2,3-dihydro-2-oxo-7-azaindole -4-carboxylate should be stored in a cool, dry, well-ventilated place, away from fire and oxidizing agents.
-Wear appropriate personal protective equipment, such as goggles and chemical protective gloves.
-Avoid contact with skin and inhalation of vapors, avoid swallowing.
-After contact occurs, immediately flush the affected area with plenty of water and seek medical help.
This information is for reference only. Please carefully study and follow the relevant safety operation guidelines and instructions when conducting any experiments or applications.
Last Update:2024-04-09 15:17:51